D-mannose 2000 mg is a unique1 product developed by Evalar experts. It contains 4 ingredients, in particular, D-mannose at a correct2 dose of 2000 mg, cranberry and bearberry extracts, as well as an organic form of magnesium citrate. They have synergistic effect preventing urinary tract infections.3 Dissolve the contents of a sachet in water to get a tasty berry-flavored drink. Another advantage is a comfortable short-term treatment course of 1 sachet/day for 7 days.3

 How do the ingredients work?

 - D-mannose has been of much interest to the European professional community for a long time. According to recent guidelines and recommendations, this is an effective remedy for urinary tract  infections. D-mannose stops pathogenic bacteria (and specifically E. coli responsible for causing most of UTIs) from sticking to the bladder and urethra walls.1

 - Cranberry has similar properties. In addition, it has antioxidant and anti-inflammatory effects, as well as improves the nutrition of the mucous membrane of the bladder and urethra.1

 - Bearberry contains arbutin, a natural antiseptic that is hydrolyzed to hydroquinone and glucose in the body. It works as a diuretic to get bacteria out of the bladder. Bearberry extract is approved by Germany’s Commission E (an analogue of the US FDA for herbal medicines) for urinary tract infections.2

 - Magnesium citrate maintains optimal urine pH, which inhibits the growth of pathogenic microbes. It enhances the properties of D-mannose and inhibits the crystallization reducing stone formation.3  This is important because people with urinary tract stones are at risk of developing bladder infections.4


 1L.A. Khodyreva, A.V. Zaitsev, A.N. Bernikov, et al. Acute and recurrent cystitis. What do we know? Russian Medical Journal. 2020; 11:69–74.

 2S.S. Krasnyak. Non-antibacterial therapy and prevention of acute and recurrent cystitis: current options and prospects. Experimental and clinical urology. 2020; 1:136–143.

 3Yu.N. Gurzhenko, V.V. Spiridonenko, E.Yu. Gurzhenko. Use of D-mannose in the treatment of inflammatory urological diseases (analytical literature review). Man’s health. 2018; 2(65): 34–38.

 4Urinary tract infections: textbook / O.V. Tirikova, I.A. Filatov; Federal State Budgetary Educational Institution of Higher Education “Irkutsk State Medical University” (IGMU) of the Ministry of Healthcare  of the Russian Federation, Department of Faculty Therapy. Irkutsk: IGMU, 2017, pp. 19–20.


Thanks to its enhanced formula, D-mannose 2000 mg developed by Evalar:3

  • prevents acute and recurrent bladder infections;

  • stops pathogenic bacteria from sticking to the mucosa of the urinary tract;

  • keeps the urinary system healthy.

The supplement is completely safe during pregnancy and lactation and can be prescribed by or under the supervision of a specialist. The sugar free drink has a natural and tasty berry flavor.

Ask for our new product in Evalar’s pharmacies and other pharmacies of the country. It is also available on our Web site and on Fitomarket.


*According to the Certificate of registration, the treatment course is 7 days.

1In the stock list of “Evalar” JSC.

2A.V. Tsareva. Acute and recurrent cystitis. Difficult patient. Russian Medical Journal. Medical review. 2021; 5(3):130-133.

3Confirmed by the Certificate of registration No. ÀÌ. of 20.07.2022