Even a small urine stone can cause excruciating pain familiar to everyone who has ever experienced renal colic. In that case, doctors take a decision about the patient’s treatment depending on the type, number, size and location of stones. They use both the latest methods of crushing or removing stones and special drugs for natural dissolving and removing of small stones, their fragments and sand. A complex of bioactive compounds found in the essential oils (terpenes) has been successfully used in the urine stones treatment in Europe for more than 60 years. Today this complex known as Cysticam developed by Evalar is produced in Russia and its price is 5 times more attractive than that of its foreign analogue.1
Among all terpenes, pinene, camphene, cineole, fenchone, borneol and anethole are of special interest. It has been confirmed that this group of compounds has synergetic effect on the urinary system that includes kidneys, ureters, bladder and urethra, in particular:2-4
Due to minimal risk of side effects, a complex of terpenes can be used in a long-term treatment to prevent stone and sand recurrence.3, 4
Cystikam, a new complex developed by Evalar is based on natural essential oils of pine (derived from pine tree needles), anise and eucalyptus, that contain standard amount of terpenes (pinenes, camphene, cineole, fenchone and anethole) enhanced with vitamin E. Due to its synergetic effect and numerous properties of active ingredients, Cystikam developed by Evalar:5
has mild diuretic, antispasmodic and anti-inflammatory effect;
dissolves small stones and sand in the kidneys and bladder eliminating them from the body;
relieves pain in patients with renal colic;
prevents stone recurrence;
improves your kidneys and bladder function.
Cysticam is suitable for both adults and children over 14 years old.5
Enteric coated capsules protect the active ingredients from dissolving in the acidic environment and prevent the stomach irritation caused by its contact with terpenes. In addition, they don’t contain any pigments and preservatives providing comfortable intake process due to a small size.
1According to the data provided by apteka.ru (Moscow) as of 11.10.2022 in comparison with dietary supplements with similar active ingredients and formulation dosage form (enteric coated capsules) as per 1 capsule.
2 E.V. Shikh. Clinical and pharmacological aspects of the use of herbal remedies in children with urinary tract diseases // Consilium Medicum. Pediatrics. 2013. No. 2, pp. 60–63.
3 V.I. Rudenko, Yu.G. Alyaev, I.G. Kraev. Medical use of plant derived terpenes in patients with urolithiasis // Effective Pharmacotherapy. Urology and Nephrology. 2019. No. 1 (1), pp. 4–9.
4 Yu.G. Alyaev, V.I. Rudenko, A.N. Perekalina, I.G. Kraev, Zh.Sh. Inoyatov. Plant derived terpenes in patients with urolithiasis // Urology. 2016. No. 2 (appendix), pp. 103–110.
5Confirmed by the Certificate of registration No. ÀÌ.01.07.01.003.R.000461.05.22 of 18.05.2022.